Stiffness of callus tissue during distraction osteogenesis

Distraction Osteogenesis

Distraction osteogenesis is increasingly used for bone lengthening of facial skeleton. Distractors may be intraoral and extraoral. The authors present development of distractors and their use for treatment of facial bones. Procedure may be used for treatment of malformations, syndroms, posttraumatic bone defects and deformities. The advantage of a distractor are a simple and fast procedure, sho...

Angiogenesis and mineralization during distraction osteogenesis.

Distraction osteogenesis is currently a standard method of bone lengthening. It is a viable method for the treatment of short extremities as well as extensive bone defects, because large amounts of bone can be regenerated in the distraction gap. Mechanical stimulation by distraction induces biological responses of skeletal regeneration that is accomplished by a cascade of biologic processes tha...

Biochemical Analysis of Callus Tissue in Osteogenesis Imperfecta Type IV

We analyzed tissue and cells from a stationary and a rapidly growing hyperplastic callus from a patient with osteogenesis imperfecta (OI) type IV and compared the results with those of compact bone and skin fibroblasts of an age-matched control. Collagen and protein contents per cell were low in the callus tissues and collagen I and III were overmodified as evidenced by an elevated level of hyd...

Distraction Osteogenesis

Distraction Osteogenesis

Distraction osteogenesis is a treatment modality for the correction of bone anomalies and abnormalities which are either pathological or developmental in origin. Its use in the field of dentistry began in the late twentieth century. Successfulresults from clinical trials has led to more researchers to explore this field. Its use in dentistry involves the correction of craniofacial anomalies, al...